Pediatric nonalcoholic fatty liver disease (NAFLD) was first reported in 1983.  It is currently the primary form of liver disease among children.  NAFLD has been associated with the metabolic syndrome, which is a cluster of risk factors that contribute to the development of cardiovascular disease and type 2 diabetes mellitus. Studies have demonstrated that abdominal obesity and insulin-resistance in particular are thought to be key contributors to the development of NAFLD.      Because obesity is becoming an increasingly common problem worldwide, the prevalence of NAFLD has been increasing concurrently.  Moreover, boys are more likely to be diagnosed with NAFLD than girls with a ratio of 2:1.   Studies have suggested that progression toward a more advance stage of disease among children is dependent on age and presence of obesity.  This finding is consistent with previous studies in adults demonstrating the same association between age and obesity, and liver fibrosis.   Early diagnosis of NAFLD in children may help prevent the development of liver disease during adulthood.   This is challenging as most children with NAFLD are asymptomatic with few showing abdominal pain.  Currently, liver biopsy is considered the gold standard for diagnosing NAFLD.  However, this method is invasive, costly and bears greater risk for children, and noninvasive screening and diagnosing methods would have significant public health implications for children with NAFLD.  The only treatment shown to be truly effective in childhood NAFLD is weight loss.  
Hey what's up. You seem like you know your stuff about liver protection and liver damage. What to you think about Phosphatidylcholine, Alpha Lipoic Acid, and Curcuminoids for the liver as well? In total, for liver health and detoxification, I take Milk Thistle (Silymarin), Siliphos Milk Thistle(Silybin), NAC, Alpha Lipoic Acid, Soya Lecithin, and Tertahydro-Curcuminoids 95%. I'm big on health sups and vitamins, so I take these and some others on a regular basis. Do you think this is good for me, or is it just making more work for my liver to filter these sups out? After reading about the TUDCA in your post, I'm thinking of using it during my next cycle. I heard SAM-E is supposed to be really good for the liver, what do you think? Alright, thanks.
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